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Parvovirus (Panleukopenia; Feline Distemper)

Written by Administrator
Saturday, 05 July 2008
The feline parvovirus is found worldwide, affecting cats in much the same way as parvovirus affects their canine counterparts. The feline parvovirus causes severe gastroenteritis in affected cats, and can be fatal unless treated with haste. This highly contagious disease primarily affects unvaccinated cats less than a year old. Spread by oral contact with infective feces, urine, or saliva, the feline parvovirus strikes the intestines with a fury, causing fever, depression, vomiting, diarrhea, abdominal pain, and dehydration. The disease can be complicated even further as bacteria within the gut proliferate as a result of the virus and release toxins into the bloodstream. The virus itself can even spread to the bone marrow and interfere with the body’s ability to mount an effective immune response to the disease. If a queen becomes infected with the parvovirus while pregnant, abortions or weak kittens could result. In many instances, these newborn kittens suffer from underdeveloped brains, causing permanent incoordination.
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The feline parvovirus is found worldwide, affecting cats in much the same way as parvovirus affects their canine counterparts. The feline parvovirus causes severe gastroenteritis in affected cats, and can be fatal unless treated with haste. This highly contagious disease primarily affects unvaccinated cats less than a year old.

Spread by oral contact with infective feces, urine, or saliva, the feline parvovirus strikes the intestines with a fury, causing fever, depression, vomiting, diarrhea, abdominal pain, and dehydration. The disease can be complicated even further as bacteria within the gut proliferate as a result of the virus and release toxins into the bloodstream. The virus itself can even spread to the bone marrow and interfere with the body’s ability to mount an effective immune response to the disease. If a queen becomes infected with the parvovirus while pregnant, abortions or weak kittens could result. In many instances, these newborn kittens suffer from underdeveloped brains, causing permanent incoordination.

Newcastle disease is an acute viral disease of domestic poultry and many other bird species. It is a worldwide problem that presents primarily as a respiratory disease, but depression, nervous manifestations, or diarrhea may be the predominant clinical form. Mortality is variable. Occurrence of a virulent form of the disease is reportable and may result in trade restrictions.

Etiology and Pathogenesis:
Newcastle disease is caused by an RNA virus, Newcastle disease virus (NDV), synonymous with avian paramyxovirus-1 which is in the genus Avulavirus , family Paramyxoviridae. Isolates are classified into 1 of 3 virulence groups by chicken embryo and chicken inoculation as virulent (velogenic), moderately virulent (mesogenic), or of low virulence (lentogenic). Lentogenic strains are used widely as live vaccines in healthy chickens. Clinical manifestations vary from high morbidity and mortality to asymptomatic infections. The severity of an infection is dependent on virus virulence and the age, immune status, and susceptibility of the host species. Chickens are the most and waterfowl the least susceptible of domestic poultry.