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Category Article Pets Animals Blastomycosis
Category Article Pets Animals Blastomycosis 
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Definition
Blastomycosis is a systemic fungal infection that usually originates in the lungs and then disseminates to order organ systems. Etiology Blastomycosis is caused by dimorphic fungus Blastomyces dermatitidis. Infection usually occurs by inhalation of infection conidiophores from environment. Water plays important role in the spread of the disease. Patophysiology
Species Dogs: large breed dogs weighing ≤ 25 kg, especially sporting breeds, may reflect exposure rather than susceptibility. Most common 2–4 years of age, uncommon after 7 years of age and disease predominant in male’s dogs. Clinical presentation/signs Ocular sign include conjungtivitis, corneal oedema, corneal vascularization, anisacoria, secondary glaucoma,anterior uveitis, granulomatous skin lesions, exopthalmos, optic neuritis. Diagnosis Diagnosis is based on the identification of the characteristic yeast within lesions, espectially within infected lymph nodes, skin and eyes. Serologic test are availablein endemic areas. Differential Diagnosis
Treatment Itraconazole ·Dogs: 5 mg/kg PO q12h with a fat-rich meal, such as canned dog food, for the first 3 days to achieve a therapeutic blood concentration as soon as possible; then reduce to once a day ·Cats: 5 mg/kg PO q12h; open the 100-mg capsules containing pellets and mix with palatable food ·Treat for a minimum of 60 days or for 1 month after all signs of disease have disappeared. Ketonazole and amphotericin B are effective in treating some cases of canine blastomycosis. Management/Prevention Location of environmental growth of Blastomyces organisms unknown; thus difficult to avoid exposure, restricting exposure to lakes and streams could be done but is not very practical. Dogs that recover from the infection are probably immune to reinfection. Tags: Article Pets Animals Blastomycosis |
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